I've tried to do this before but I've never managed to get the realtone cable hack to allow me to use ASIO on my Focusrite 2i2 so I have to stick to my official cable. This is more of a sidenote but could be of interest for those looking at audio routing. I revisited this yesterday after this post reminded me, I did more searching and discovered SAR (Synchronous Audio Router). If you have an audio device with a genuine ASIO driver (not ASIO4all emulation) you can create virtual endpoints, (inputs and outputs that show up as audio devices in Windows as long as the DAW is running) to route sound into and out of your DAW, I managed to route a web browser and Rocksmith game audio into my DAW, in seconds compared to the hoops I used to have to jump through with Voicemeeter Banana. I use Ableton Live 10 but reaper works well as will probably any DAW. This routing happens faster than ASIO to ensure the low ASIO latency stream works. If you do have a look at SAR just be aware that SAR's automatic application routing no longer works on W10 due to the changes made to audio routing in the Spring Update. So once an endpoint has been created, the application will need to be routed using the Windows Sound Settings. Unfortunately after all of this I'm still unable to get an input into Rocksmith from my Focusrite 2i2, so wish I'd waited and bought the 2nd gen.