Hey Wndwlicker...lol at name... I play bass as well. I currently have a Ampeg BA112 studio Amp, which is why I want to use that, but still have a feed going thru my PC for Rocksmith as well. I noticed while playing a song I THOUGHT I had down thru Rocksmith PC, when I played thru my Amp I was sloppy as hell. So rather than learn bad habits because I cant hear them that well thru PC, I want to play thru amp so all the nasties can be addressed as soon as I hear them! firekorn...ya I did hear groundloop can be a problem. But for now I dont use any effects pedals, only the built in EQ and distortion I have in my amp. So I will just have to experiment. I also read going from guitar > a decent inline tuner > ABY can eliminate that ground loop.