In my case I named it "Rocksmith USB Guitar Adapter". If the standard audio settings on Mac do not work because you have a multichannel device I can also recommend Rogue Amoeba Loopback https://rogueamoeba.com/loopback/
This allows to take explicitly certain channels of a multi channel audio device and map it to the new virtual "Rocksmith USB Guitar Adapter". It was ok, that the new device always has stereo output. I managed to connect Rocksmith that way with a MOTU AVB device and also an AXE FX The sound is much better now than the standard cable!!