Go to your library on Steam, open Rocksmith's properties menu, enter the beta code "JustInCaseWeNeedIt," and after it installs run the latest version of RSBypass
I was able to get my CDLC working again by using the JustInCaseWeNeed it beta and then using the newest RSBypass again (https://github.com/aik002/RSBypass). But I'm running Catalina, not sure about newer OSXs.