Playing a lot of Rocksmith has got me listening to guitar, and music in general, in a more nuanced way. Now some guitarists I wasn't interested in sound great to me, and my listening preferences have opened up to new genres.

 

One guitarist I never really enjoyed was The Edge from U2, but now I have a lot of respect for what he does. A new genre I've always kinda sorta enjoyed that I'm really loving now is the Chicago Blues, and a new guitarist I discovered in that genre is Guitar Shorty, who I highly recommend. 

 

Anyone else experience changes in their musical preferences since picking up Rocksmith (or just learning an instrument, I guess)?

Moved to off-topic :)

I wouldn't say my music taste has changed but it's definitely expanded. I'm from a prog rock/ metal and grunge background when it comes to my favorite flavors, but, since playing bass I've definitely added more genre's to my taste, my favorite bassists are Geddy Lee, Les Claypool and a couple of session musicians, Josh Fossgreen and Jay Mentzino (Holt). I've always enjoyed funk and soul, so, the opportunity to play some has opened my eyes to a lot of techniques that I would never have necessarily tried. John Deacon of Queen, despite being a fan of the band, I never rated that much until playing the bass and realised he's a terrific bassist, but that was down to naivety more than not paying attention, I always enjoyed Queen's bass lines and to play them has improved my shifting technique up and down the neck :) I'll have to try some U2, although I'm not a fan of them in the slightest I think you have to give some bands that you don't like a chance, as you might miss out on a really enjoyable riff/phrase :)

Hank Marvin!

When it's just about playing guitar i adore Fred Brum and Tosin Abasi, eventhough it's no music to listen to day in day out.