Using the following: PC to 1080p TV Scarlett 2i4 Marshall DSL40c Digitech GSP1101 AB Switch Guitar to AB Switch, B is RealTone Cable to PC, A is to Amp and Effects. I use the onboard sound for Rocksmith and the Scarlett 2i4 for Amp and Effects. Turn down the instrument volume in Rocksmith when I want to play along with my Amp and Effects. https://drive.google.com/open?id=0B8N2L0obypt8cUVyQkdhQlBrTnc