I had the same problem, memory error (but mine caused my computer to crash). And replacing the dll file works until I restart the computer. Rocksmith is running all through the virtual memory (task manager should be able to tell you), but the memory its allocating isn't associated with Rocksmith itself. I had increased this to huge numbers but it still hit eventually, and every time I close Rocksmith after it was still using most of the virtual memory. Suggesting some kind of memory leak. windows 10 and ~350 cldc.